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Transgene Detail
Symbol: Tg(CMV-GFP,-BBS4)4T25Vcs
Name: transgene insertion 4T25, Val C Sheffield
MGI ID: MGI:5432908
Synonyms: Bbs4-pLAP, LAP-BBS4
Transgene: Tg(CMV-GFP,-BBS4)4T25Vcs  Location: unknown  
Strain of Origin:  C57BL/6J x SJL/J
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Tg(CMV-GFP,-BBS4)4T25Vcs expresses 1 gene
Mutation detailsHuman BBS4 and a LAP tag (GFP followed by a cleavage site for Tobacco Etch Virus (TEV) protease and an S-tag) were placed under the control of cytomegalovirus (CMV) immediate early (IE94) promoter in a transgenic vector. Three lines were generated with the highest expression level in line 4T25. (J:177990)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:177990 Seo S, et al., A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened. PLoS Genet. 2011 Nov;7(11):e1002358
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory