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Ddit4tm1.1Sinc
Targeted Allele Detail
Nomenclature
Symbol: Ddit4tm1.1Sinc
Name: DNA-damage-inducible transcript 4; targeted mutation 1.1, Andrew Sinclair
MGI ID: MGI:5432482
Gene: Ddit4  Location: Chr10:59949675-59951770 bp, - strand  Genetic Position: Chr10, 29.66 cM, cytoband B3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186462
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. A neo cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed the coding sequence and the neo cassette. (J:186462)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddit4 Mutation:  5 strains or lines available
References
Original:  J:186462 Notini AJ, et al., Redd1 is a novel marker of testis development but is not required for normal male reproduction. Sex Dev. 2012;6(5):223-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory