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Transgene Detail
Symbol: Tg(tetO-GLI1)10Rup
Name: transgene insertion 10, J Ruppert
MGI ID: MGI:5432196
Synonyms: TRE-GLi1
Transgene: Tg(tetO-GLI1)10Rup  Location: unknown  
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Mutation:    Insertion
Tg(tetO-GLI1)10Rup expresses 1 gene
Mutation detailsThe 5.7 kB transgenic construct contains a tetracycline responsive element (TRE or tetO), the minimal human cytomegalovirus promoter, and an HA-tagged wildtype human GLI1, GLI1-Kruppel family member GLI1. (J:186380)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:186380 Li X, et al., Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation. Oncogene. 2006 Jan 26;25(4):609-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory