Tg(Camk2a-tTA)2Stl
Transgene Detail

Summary

• Symbol: Tg(Camk2a-tTA)2Stl
• Name: transgene insertion 2, Susumu Tonegawa
• MGI ID: MGI:5432122
• Synonyms: Tg2 line2
• Transgene: Tg(Camk2a-tTA)2Stl Location: unknown
• Alliance: Tg(Camk2a-tTA)2Stl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgene construct contained the tetracycline transactivator (tTA) coding sequence downstream of a loxP-STOP-loxP fragement. This was inserted downstream of the alpha-CamKII (Camk2a) promoter in the final construct. A founder linse 1 and 2 were established. (J:131852)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:186102 Nakashiba T, et al., Young dentate granule cells mediate pattern separation, whereas old granule cells facilitate pattern completion. Cell. 2012 Mar 30;149(1):188-201
• All: 2 reference(s)