Tg(Erv4-tdTomato)449Slp
Transgene Detail

Summary

• Symbol: Tg(Erv4-tdTomato)449Slp
• Name: transgene insertion 449, Samuel L Pfaff
• MGI ID: MGI:5431576
• Synonyms: 2C::tdtomato, MERVL::tdtomato, Tg(MERVL-tdTomato)449Slp
• Transgene: Tg(Erv4-tdTomato)449Slp Location: unknown
• Alliance: Tg(Erv4-tdTomato)449Slp page

Transgene origin

• Strain of Origin: BALB/c and C57BL/6

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains the 5' LTR of murine endogenous retrovirus with leucine tRNA primer (MuERV-L, also called MERVL and Erv4), the primer binding site, and a portion of the Gag gene upstream of the red fluorescent protein tandem dimeric Tomato (tdTomato). Line 449 was generated. (J:186302)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:186302 Macfarlan TS, et al., Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 2012 Jul 5;487(7405):57-63
• All: 2 reference(s)