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Tg(Dyrk1a)189N3Yah
Transgene Detail
Nomenclature
Symbol: Tg(Dyrk1a)189N3Yah
Name: transgene insertion 189N3, Yann Herault
MGI ID: MGI:5430362
Synonyms: mBACtgDyrk1a, Tg(Dyrk1a)#Jmd
Transgene: Tg(Dyrk1a)189N3Yah  Location: unknown  
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:182294
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Dyrk1a)189N3Yah expresses 1 gene
 
Mutation detailsThis transgene consists of a 152 kb bacterial artificial chromosome clone, 189N3, containing the whole mouse Dyrk1a gene with a 6 kb flanking fragment on the 5' side and a 19 kb flanking fragment on the 3' side and retrofitted to containa a PGKneo cassette (189N3 BAC clone from Research Genetics). The clone contains only the Dyrk1a gene and this transgene contains one extra copy of Dyrk1a. (J:182294)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:182294 Guedj F, et al., DYRK1A: A master regulatory protein controlling brain growth. Neurobiol Dis. 2012 Apr;46(1):190-203
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory