Snca^tm1Mjff
Targeted Allele Detail

Summary

• Symbol: Snca^tm1Mjff
• Name: synuclein, alpha; targeted mutation 1, The Michael J Fox Foundation
• MGI ID: MGI:5429537
• Gene: Snca Location: Chr6:60708559-60806839 bp, - strand Genetic Position: Chr6, 29.15 cM
• Alliance: Snca^tm1Mjff page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185638
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector containing a floxed NEO cassette was used to disrupt exons 1 through 4. Correctly targeted chimeric animals were crossed to C57BL/6NTac-Gt(ROSA)26Sor^{tm16(cre)Arte} mice to remove the floxed NEO cassette. (J:185638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Snca Mutation: 34 strains or lines available

Notes

The was created in B6-3 embryonic stem (ES) cells.

References

• Original: J:185638 The Michael J. Fox Foundation, A targeted mutation of the Snca (synuclein, alpha) gene. MGI Direct Data Submission. 2012
• All: 10 reference(s)