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Ak8Gt(OST16378)Lex
Gene trapped Allele Detail
Nomenclature
Symbol: Ak8Gt(OST16378)Lex
Name: adenylate kinase 8; gene trap OST16378, Lexicon Genetics
MGI ID: MGI:5429197
Gene: Ak8  Location: Chr2:28700164-28813165 bp, + strand  Genetic Position: Chr2, 19.38 cM
Mutation
origin
Mutant Cell Line:  OST16378 (Lexicon Genetics)
Germline Transmission:  Earliest citation of germline transmission: J:185566
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector
    A gene trap vector inserted into intron 5. (J:185566)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ak8 Mutation:  3 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Hydrocephalus in homozygous mice (J:185566)

References
Original:  J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory