Htr2c^tm2Lex
Targeted Allele Detail

Summary

• Symbol: Htr2c^tm2Lex
• Name: 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 2, Lexicon Genetics
• MGI ID: MGI:5429022
• Gene: Htr2c Location: ChrX:145745509-145980273 bp, + strand Genetic Position: ChrX, 68.46 cM, cytoband D-F4
• Alliance: Htr2c^tm2Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185494
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 4 was deleted. (J:185494)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htr2c Mutation: 12 strains or lines available

References

• Original: J:185494 Brommage R, et al., High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes. Obesity (Silver Spring). 2008 Oct;16(10):2362-7
• All: 1 reference(s)