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Tg(Krt15-TK)32Cot
Transgene Detail
Summary
Symbol: Tg(Krt15-TK)32Cot
Name: transgene insertion 32, George Cotsarelis
MGI ID: MGI:5428878
Synonyms: Krt1-15-HSV-TK
Transgene: Tg(Krt15-TK)32Cot  Location: unknown  
Alliance: Tg(Krt15-TK)32Cot page
Transgene
origin
Strain of Origin:  (C57BL/6J x SJL/J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe HSV-1 thymidine kinase (TK) sequence was cloned into a construct containing the Krt15 (Krt1-15). The purified contruct was injected into fertilized (C57BL/6J x SJL/J)F2 oocytes. 6 founders were generated and lines 32 (2 copies of transgene) and 45 (3 copies) were used for further studies. (J:146740)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:146740 Ito M, et al., Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med. 2005 Dec;11(12):1351-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory