About   Help   FAQ
Wnk4tm1Pfi
Targeted Allele Detail
Nomenclature
Symbol: Wnk4tm1Pfi
Name: WNK lysine deficient protein kinase 4; targeted mutation 1, Pfizer, Ltd
MGI ID: MGI:5427702
Gene: Wnk4  Location: Chr11:101260567-101277409 bp, + strand  Genetic Position: Chr11, 64.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184790
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Generation of the Wnk4tm1Pfi allele
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnk4 Mutation:  4 strains or lines available
Notes
ES cell line - TG-ES01-01 ESM07

References
Original:  J:184790 Castaneda-Bueno M, et al., Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7929-34
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/23/2014
MGI 5.19
The Jackson Laboratory