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Targeted Allele Detail
Symbol: Pdcd1lg2tm2Dmp
Name: programmed cell death 1 ligand 2; targeted mutation 2, Drew M Pardoll
MGI ID: MGI:5427625
Gene: Pdcd1lg2  Location: Chr19:29410919-29471157 bp, + strand  Genetic Position: Chr19, 23.93 cM, cytoband C2-C3
Germline Transmission:  Earliest citation of germline transmission: J:99212
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe signal peptide containing the ATG initiation codon was replaced with EGFP and a NEO cassette. This allele was subsequently used to generate Pdcd1lg2tm1Dmp. (J:99212)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdcd1lg2 Mutation:  8 strains or lines available
Original:  J:99212 Shin T, et al., In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. J Exp Med. 2005 May 16;201(10):1531-41
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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