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Htttm6Xen
Targeted Allele Detail
Nomenclature
Symbol: Htttm6Xen
Name: huntingtin; targeted mutation 6, Taconic Biosciences
MGI ID: MGI:5426952
Synonyms: Htttm6(HTT*Q105)Xen
Gene: Htt  Location: Chr5:34919084-35069878 bp, + strand  Genetic Position: Chr5, 17.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147112
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA construct carrying human exon 1 of Huntington gene with 21 CAG CAA CAG CAA CAA repeats (~105 glutamine expansions) was targeted to mouse Huntington gene replacing mouse exon 1 of the gene. (J:147112)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htt Mutation:  121 strains or lines available
References
Original:  J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory