Casp6^tm1.1Xen
Targeted Allele Detail

Summary

• Symbol: Casp6^tm1.1Xen
• Name: caspase 6; targeted mutation 1.1, Taconic Biosciences
• MGI ID: MGI:5426935
• Gene: Casp6 Location: Chr3:129695074-129707752 bp, + strand Genetic Position: Chr3, 59.5 cM, cytoband H1
• Alliance: Casp6^tm1.1Xen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sequences flanking the first through fourth coding exons and loxP sequences flanking the Neo expression cassette were targeted to the Caspase 6 gene. In-vitro mediated cre-deleted resulted in removal of neo cassette leaving two lox P sites flanking coding exons 1 to 4 (or exons 2 to 5 if the first non-coding exon is included). (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Casp6 Mutation: 15 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)