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Gt(ROSA)26Sortm49(HTT)Arte
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm49(HTT)Arte
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 49, TaconicArtemis
MGI ID: MGI:5426929
Synonyms: N536-Q148
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147112
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, RMCE-ready)
Mutation:    Insertion
 
Mutation detailsA cDNA construct carrying mutant Huntington gene (145Q) truncated at position aa S536 under the control of the CMV early enhancer/chicken beta actin promoter was targeted into Gt(ROSA)26Sor locus by RMCE. (J:147112, J:243843)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  741 strains or lines available
References
Original:  J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory