About   Help   FAQ
CasrBCH007
Chemically induced Allele Detail
Nomenclature
Symbol: CasrBCH007
Name: calcium-sensing receptor; bone calcium high mutant 007
MGI ID: MGI:5424982
Gene: Casr  Location: Chr16:36493696-36562141 bp, - strand  Genetic Position: Chr16, 25.57 cM
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThis ENU-induced mutation was isolated in a screen for metabolic bone disease as part of the Munich ENU Mutagenesis Project. Missense mutation in exon 4 of the gene, a T-to-C point mutation at position 626 of the cDNA is predicted to alter codon 208 in the encoded protein from a valine to an alanine. (J:183993)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Casr Mutation:  28 strains or lines available
References
Original:  J:183993 Sabrautzki S, et al., New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. Mamm Genome. 2012 Aug;23(7-8):416-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/12/2018
MGI 6.12
The Jackson Laboratory