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Acta1tm1Hrd
Targeted Allele Detail
Nomenclature
Symbol: Acta1tm1Hrd
Name: actin, alpha 1, skeletal muscle; targeted mutation 1, Edna C Hardeman
MGI ID: MGI:5424775
Synonyms: Acta1(H40Y), Acta1tm1(H40Y;neo)Hrd
Gene: Acta1  Location: Chr8:123891767-123894736 bp, - strand  Genetic Position: Chr8, 72.26 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184588
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Single point mutation
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Acta1 Mutation:  20 strains or lines available
References
Original:  J:184588 Nguyen MA, et al., Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy. Brain. 2011 Dec;134(Pt 12):3516-29
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory