Mir196a-2tm1Wtsi
Targeted Allele Detail
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Symbol: |
Mir196a-2tm1Wtsi |
Name: |
microRNA 196a-2; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5320133 |
Synonyms: |
Mir196a-2tm1(mirKO)Wtsi |
Gene: |
Mir196a-2 Location: Chr15:102881785-102881869 bp, + strand Genetic Position: Chr15, 58.04 cM
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Alliance: |
Mir196a-2tm1Wtsi page
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Mutant Cell Line: |
mirKO_ES_PuDtk_13C1 |
Germline Transmission: |
Earliest citation of germline transmission:
J:226712
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
Sanger miRNA knockouts
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
Vector: PGK_EM7_PuDtk_bGHpA
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Mutation details: The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion of size 79 starting at position 102879591 and ending at position 102879670 of Chromosome 15 (Build GRCm39). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and finally an FRT site.
(J:174268)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mir196a-2 Mutation: |
2 strains or lines available
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Original: |
J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5 |
All: |
2 reference(s) |
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