Mir7-2tm1Wtsi
Targeted Allele Detail
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Symbol: |
Mir7-2tm1Wtsi |
Name: |
microRNA 7-2; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5319953 |
Synonyms: |
Mir7-2tm1(mirKO)Wtsi |
Gene: |
Mir7-2 Location: Chr7:78538025-78538121 bp, + strand Genetic Position: Chr7, 44.83 cM
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Mutant Cell Lines: |
mirKO_ES_PuDtk_7G1, mirKO_ES_PuDtk_20G2, mirKO_ES_PuDtk_20G3 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
Sanger miRNA knockouts
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
Vector: PGK_EM7_PuDtk_bGHpA
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Mutation details: The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion of size 140 starting at position 78538010 and ending at position 78538150 of Chromosome 7 (Build GRCm39). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and finally an FRT site.
(J:174268)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mir7-2 Mutation: |
3 strains or lines available
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Original: |
J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5 |
All: |
1 reference(s) |
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