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Tg(Slc1a3-DsRed)593Dbe
Transgene Detail
Summary
Symbol: Tg(Slc1a3-DsRed)593Dbe
Name: transgene insertion 593, Dwight E Bergles
MGI ID: MGI:5319545
Synonyms: Glast-DsRed
Transgene: Tg(Slc1a3-DsRed)593Dbe  Location: unknown  
Alliance: Tg(Slc1a3-DsRed)593Dbe page
Transgene
origin
Strain of Origin:  B6SJLF1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA BAC reporter construct was made in which DsRed was inserted downstream of the Slc1a3 (GLAST) promoter. Offspring from two of the founders (lines 593 and 570) exhibited high DsRed expression, whereas offspring from the third (line 573) expressed DsRed at a much lower level. DsRed expression in these mice was low in the cerebellar cortex but high in the cerebellum. (J:182127)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:182127 Regan MR, et al., Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS. J Neurosci. 2007 Jun 20;27(25):6607-19
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory