About   Help   FAQ
Pink1tm1Vbae
Targeted Allele Detail
Summary
Symbol: Pink1tm1Vbae
Name: PTEN induced putative kinase 1; targeted mutation 1, Veerle Baekelandt
MGI ID: MGI:5319215
Gene: Pink1  Location: Chr4:138040720-138053618 bp, - strand  Genetic Position: Chr4, 70.14 cM
Alliance: Pink1tm1Vbae page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182977
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exon 1. RT-PCR confirmed the absence of transcript expression in the brain and mouse embryonic fibroblasts. (J:182977)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pink1 Mutation:  42 strains or lines available
References
Original:  J:182977 Heeman B, et al., Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance. J Cell Sci. 2011 Apr 1;124(Pt 7):1115-25
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory