About   Help   FAQ
Fbxo4tm1Kei
Targeted Allele Detail
Nomenclature
Symbol: Fbxo4tm1Kei
Name: F-box protein 4; targeted mutation 1, Keiichi I Nakayama
MGI ID: MGI:5319202
Gene: Fbxo4  Location: Chr15:3965445-3979573 bp, - strand  Genetic Position: Chr15, 1.84 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183656
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES-lacZ/neo cassette replaced exon 1 (downstream of the translation initiation site) through exon 5. RT-PCR confirmed the absence of transcript expression in mouse embryonic fibroblasts. (J:183656)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fbxo4 Mutation:  13 strains or lines available
References
Original:  J:183656 Kanie T, et al., Genetic reevaluation of the role of F-box proteins in cyclin D1 degradation. Mol Cell Biol. 2012 Feb;32(3):590-605
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2020
MGI 6.15
The Jackson Laboratory