Stat1^tm1.1Mmul
Targeted Allele Detail

Summary

• Symbol: Stat1^tm1.1Mmul
• Name: signal transducer and activator of transcription 1; targeted mutation 1.1, Mathias Muller
• MGI ID: MGI:5319173
• Synonyms: Stat1^fl, Stat1^tm1(fl)
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^tm1.1Mmul page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183580
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 6. A floxed neo cassette was inserted downstream of exon 10. Cre-mediated recombination removed the neo cassette and left exons 6 through 10 floxed. (J:183580)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 72 strains or lines available

References

• Original: J:183580 Wallner B, et al., Generation of mice with a conditional Stat1 null allele. Transgenic Res. 2012 Feb;21(1):217-24
• All: 11 reference(s)