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Tg(TERT-rluc)DJzhu
Transgene Detail
Nomenclature
Symbol: Tg(TERT-rluc)DJzhu
Name: transgene insertion D, Jiyue Zhu
MGI ID: MGI:5318989
Synonyms: hTERT-Renilla luciferase reporter
Transgene: Tg(TERT-rluc)DJzhu  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/NJ
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe 158 kb human bacterial artificial chromosome (BAC) RPCI11-117B23 containing CLPTM1L (CLPTM1-like), TERT (telomerase reverse transcriptase) and SLC6A18 (solute carrier family 6, member 18) genes, was modified by inserting a codon optimized Renilla reniformis luciferase ORF at the TERT ATG codon. The BAC vector may contain loxP/lox511 sequences. (J:182426)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:182426 Jia W, et al., A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis. FASEB J. 2011 Mar;25(3):979-89
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory