About   Help   FAQ
Tg(Zfp423-EGFP)7Brsp
Transgene Detail
Nomenclature
Symbol: Tg(Zfp423-EGFP)7Brsp
Name: transgene insertion 7, Bruce M Spiegelman
MGI ID: MGI:5318774
Synonyms: Zfp423GFP
Transgene: Tg(Zfp423-EGFP)7Brsp  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsCoding sequence of EGFP followed by a polyadenylationsignal was inserted into the initiation codon of Zfp423 located in exon 1 from bacterial artificial chromosome RP23-102G4. The modified BAC does not contain any functional domains of Zfp423 or contain full-length coding sequence of any other annotated genes. Five founder lines were produced, two of which were greatly enriched for Zfp423 mRNA in cells positive for EGFP. Data for one of these two lines was published. (J:182285)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:182285 Gupta RK, et al., Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 2012 Feb 8;15(2):230-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory