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Transgene Detail
Symbol: Tg(Zfp423-EGFP)7Brsp
Name: transgene insertion 7, Bruce M Spiegelman
MGI ID: MGI:5318774
Synonyms: Zfp423GFP
Transgene: Tg(Zfp423-EGFP)7Brsp  Location: unknown  
Strain of Origin:  FVB/N
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsCoding sequence of EGFP followed by a polyadenylationsignal was inserted into the initiation codon of Zfp423 located in exon 1 from bacterial artificial chromosome RP23-102G4. The modified BAC does not contain any functional domains of Zfp423 or contain full-length coding sequence of any other annotated genes. Five founder lines were produced, two of which were greatly enriched for Zfp423 mRNA in cells positive for EGFP. Data for one of these two lines was published. (J:182285)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:182285 Gupta RK, et al., Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 2012 Feb 8;15(2):230-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory