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Slamf6tm1Pls
Targeted Allele Detail
Nomenclature
Symbol: Slamf6tm1Pls
Name: SLAM family member 6; targeted mutation 1, Pamela L Schwartzberg
MGI ID: MGI:5318529
Synonyms: Ly108-
Gene: Slamf6  Location: Chr1:171917515-171953170 bp, + strand  Genetic Position: Chr1, 79.54 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183088
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA stop codon was introduced into exon 2 and replaced part of exons 2 and 3 with a neo cassette. Flow cytometry confirmed the absence of protein expression. (J:183088, J:193308)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slamf6 Mutation:  3 strains or lines available
Notes
ES cell line = HGTC-8 (C57BL/6J)

References
Original:  J:183088 Dutta M, et al., Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108. J Immunol. 2012 Apr 1;188(7):3031-41
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory