Tg(Igh-Mir155)#Cro
Transgene Detail

Summary

• Symbol: Tg(Igh-Mir155)#Cro
• Name: transgene insertion, Carlo M Croce
• MGI ID: MGI:5317462
• Synonyms: Emu/VH Mir155
• Transgene: Tg(Igh-Mir155)#Cro Location: unknown
• Alliance: Tg(Igh-Mir155)#Cro page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh-Mir155)#Cro expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir155 (MGI:2676840)

• Mutation details: The IgH Emu enhancer drives late pro-B cell-specific expression of the mouse microRNA followed by the 3'UTR and polyadenylation sequence from the human beta-globin gene. Eight founders were established generating several lines (lines 8 through 15). The pound symbol (#) is used when no line is specified and/or lines are pooled. Northern blot analysis confirmed transcript expression in the spleen. (J:109591)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:160573 Volinia S, et al., Reprogramming of miRNA networks in cancer and leukemia. Genome Res. 2010 May;20(5):589-99
• All: 6 reference(s)