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Targeted Allele Detail
Symbol: Fblim1tm1.2Ref
Name: filamin binding LIM protein 1; targeted mutation 1.2, Reinhard Fassler
MGI ID: MGI:5317180
Synonyms: migfillin-
Gene: Fblim1  Location: Chr4:141576062-141606052 bp, - strand  Genetic Position: Chr4, 74.64 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:182886
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsCre-mediated recombination of Fblim1tm1.1Ref removed exons 2 and 3. Western blot analysis confirmed the absence of protein expression in heart and lung extracts. (J:182886)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fblim1 Mutation:  77 strains or lines available
Original:  J:182886 Moik DV, et al., Loss of migfilin expression has no overt consequences on murine development and homeostasis. J Cell Sci. 2011 Feb 1;124(Pt 3):414-21
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory