Fblim1^tm1.1Ref
Targeted Allele Detail

Summary

• Symbol: Fblim1^tm1.1Ref
• Name: filamin binding LIM protein 1; targeted mutation 1.1, Reinhard Fassler
• MGI ID: MGI:5317179
• Gene: Fblim1 Location: Chr4:141303373-141333351 bp, - strand Genetic Position: Chr4, 74.64 cM, cytoband E1
• Alliance: Fblim1^tm1.1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182886
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette and left exons 2 and 3 floxed. (J:182886)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fblim1 Mutation: 82 strains or lines available

References

• Original: J:182886 Moik DV, et al., Loss of migfilin expression has no overt consequences on murine development and homeostasis. J Cell Sci. 2011 Feb 1;124(Pt 3):414-21
• All: 1 reference(s)