Gtf2i^tm1Uta
Targeted Allele Detail

Summary

• Symbol: Gtf2i^tm1Uta
• Name: general transcription factor II I; targeted mutation 1, Uta Francke
• MGI ID: MGI:5317124
• Gene: Gtf2i Location: Chr5:134266688-134343614 bp, - strand Genetic Position: Chr5, 74.48 cM
• Alliance: Gtf2i^tm1Uta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182796
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• A neo cassette, loxP site and 5' portion of the Hprt minigene were inserted into intron 32. (J:182796)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gtf2i Mutation: 138 strains or lines available

References

• Original: J:182796 Li HH, et al., Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice. EMBO Mol Med. 2009 Apr;1(1):50-65
• All: 1 reference(s)