Limk1^tm1Uta
Targeted Allele Detail

Summary

• Symbol: Limk1^tm1Uta
• Name: LIM domain kinase 1; targeted mutation 1, Uta Francke
• MGI ID: MGI:5317122
• Gene: Limk1 Location: Chr5:134684893-134717452 bp, - strand Genetic Position: Chr5, 74.73 cM, cytoband G2
• Alliance: Limk1^tm1Uta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182796
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutations: Duplication, Insertion
• Limk1^tm1Uta involves 1 genes/genome features (Limk1) View all
• Mutation details: A neo cassette, loxP site and the 5' portion of the Hprt minigene were inserted into intron 2 duplicating exons 3 and 4. (J:182796)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Limk1 Mutation: 28 strains or lines available

References

• Original: J:182796 Li HH, et al., Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice. EMBO Mol Med. 2009 Apr;1(1):50-65
• All: 1 reference(s)