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Tg(tetO-ATXN1*82Q)#Horr
Transgene Detail
Nomenclature
Symbol: Tg(tetO-ATXN1*82Q)#Horr
Name: transgene insertion, Harry T Orr
MGI ID: MGI:5317077
Synonyms: TRE-SCA1[82Q]
Transgene: Tg(tetO-ATXN1*82Q)#Horr  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-ATXN1*82Q)#Horr expresses 1 gene
 
Mutation detailsThis transgene consists of the human ATXN1 (SCA1) cDNA encoding a mutant polyglutamine tract with 82 repeats joined to the TRE element. Seven founders were generated and the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:95453)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:95453 Zu T, et al., Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice. J Neurosci. 2004 Oct 6;24(40):8853-61
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory