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Hoxa13tm1.1(cre)Makm
Targeted Allele Detail
Nomenclature
Symbol: Hoxa13tm1.1(cre)Makm
Name: homeobox A13; targeted mutation 1.1, Marie Kmita
MGI ID: MGI:5316384
Synonyms: Hoxa13Cre, Hoxa13:Cre
Gene: Hoxa13  Location: Chr6:52258853-52260880 bp, - strand  Genetic Position: Chr6, 25.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181230
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA cre-IRES-VenusGFP cassette followed by SV40 666bp sequence and neomycin cassette flanked by two Frt sites and a loxP site was inserted at ATG of Hoxa13 gene and entire first exon was replaced.F1 offspring were intercrossed with homozygous FLPeR mice to delete the neomycin cassette. (J:181230, J:224090)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hoxa13     Summary of all recombinase alleles driven by Hoxa13.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa13 Mutation:  22 strains or lines available
References
Original:  J:181230 Scotti M, et al., Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals. Development. 2012 Feb;139(4):731-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory