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Hprt1tm1(Trp53RE-EGFP)Dpl
Targeted Allele Detail
Summary
Symbol: Hprt1tm1(Trp53RE-EGFP)Dpl
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, David P Lane
MGI ID: MGI:5315856
Synonyms: p21p53RE-EGFP
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1tm1(Trp53RE-EGFP)Dpl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182031
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
    The Trp53 response element from Cdkn1a and a delta fos minimal promoter drives expression of EGFP. (J:182031)
Generation of the Hprt1tm1(Trp53RE-EGFP)Dpl allele
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1272 strains or lines available
References
Original:  J:182031 Goh AM, et al., Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1685-90
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory