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Spontaneous Allele Detail
Symbol: Wnt7apx-J
Name: wingless-type MMTV integration site family, member 7A; postaxial hemimelia Jackson
MGI ID: MGI:5315307
Gene: Wnt7a  Location: Chr6:91363981-91411363 bp, - strand  Genetic Position: Chr6, 40.45 cM
Strain of Origin:  C57BL/6J
Allele Type:    Spontaneous
Mutations:    Deletion, Single point mutation
Mutation detailsThis spontaneous mutation in Chromosome 6 has a G to A transition at 91,344,546 (NCBI37/mm9) causing the replacement of arginine with tryptophan at amino acid 143, and also has a 23,106 bp intragenic deletion, 91,321,380 - 91,244,486, that encompasses a portion of exon 3 and removes the 5' end of intron 3 including the splice donor site. (J:188477)
Inheritance:    Recessive
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt7a Mutation:  10 strains or lines available
Original:  J:188477 Dionne L, et al., Postaxial hemimelia Jackson, a new spontaneous mouse mutation in Wnt7a. MGI Direct Data Submission. 2012;
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory