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Tg(Slc17a6-COP4*H134R/EYFP)2Oki
Transgene Detail
Nomenclature
Symbol: Tg(Slc17a6-COP4*H134R/EYFP)2Oki
Name: transgene insertion 2, Ole Kiehn
MGI ID: MGI:5314662
Synonyms: Vglut2-ChR2-YFP, vGluT2-YFP
Transgene: Tg(Slc17a6-COP4*H134R/EYFP)2Oki  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial articificial chromosone (BAC) # RPCI23-84M15 containing the mouse Vglut2 gene was modified by the introduction of a human codon-optimized channel rhodopsin (hChR2) and a gain-of-function H134R substitution fused to an enhanced yellow fluorescent protein sequence (EYFP) and inserted to inactivate the Vglut2 gene. Line 2 was generated. (J:180947)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:180947 Hagglund M, et al., Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion. Nat Neurosci. 2010 Feb;13(2):246-52
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory