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Tg(Th-FTH1)1Jkan
Transgene Detail
Nomenclature
Symbol: Tg(Th-FTH1)1Jkan
Name: transgene insertion 1, Julie Andersen
MGI ID: MGI:5314634
Transgene: Tg(Th-FTH1)1Jkan  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Th-FTH1)1Jkan expresses 1 gene
 
Mutation detailsThe transgene construct contained a 2.6kb fragment of the human FTH1 (ferritin, heavy polypeptide 1) gene lacking the iron-response element (IRE) under the control of the rat Th (tyrosine hydroxylase) promoter, and SV40 polyA signal Line 1 was generated. (J:139481)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:139481 Kaur D, et al., Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron. 2003 Mar 27;37(6):899-909
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory