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Rras2tm1Itl
Targeted Allele Detail
Nomenclature
Symbol: Rras2tm1Itl
Name: related RAS viral (r-ras) oncogene 2; targeted mutation 1, inGenious Targeting Laboratory
MGI ID: MGI:5314105
Gene: Rras2  Location: Chr7:114046782-114117781 bp, - strand  Genetic Position: Chr7, 59.29 cM, cytoband F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181730
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 2 through 4. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:181730)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rras2 Mutation:  18 strains or lines available
References
Original:  J:181730 Singh G, et al., R-Ras is required for murine dendritic cell maturation and CD4+ T-cell priming. Blood. 2012 Feb 16;119(7):1693-701
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory