Mlh3^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Mlh3^{tm1(KOMP)Vlcg}
• Name: mutL homolog 3; targeted mutation 1, Velocigene
• MGI ID: MGI:5312527
• Gene: Mlh3 Location: Chr12:85281294-85317373 bp, - strand Genetic Position: Chr12, 39.61 cM
• Alliance: Mlh3^{tm1(KOMP)Vlcg} page
• IMPC: Mlh3 gene page

Mutation origin

• Mutant Cell Lines: 19262A-D5, 19262A-F6, 19262A-F11, 19262A-G10
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 33804bp between positions 85282378-85316181 of Chromosome 12 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Mlh3 Mutation: 78 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)