Gsdmd^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Gsdmd^{tm1(KOMP)Vlcg}
• Name: gasdermin D; targeted mutation 1, Velocigene
• MGI ID: MGI:5312478
• Gene: Gsdmd Location: Chr15:75734176-75739257 bp, + strand Genetic Position: Chr15, 35.0 cM, cytoband D3-E1
• IMPC: Gsdmd gene page

Mutation origin

• Mutant Cell Lines: 19165A-A5, 19165A-B4, 19165A-B11, 19165A-C3, 19165A-H12
• Germline Transmission: Unknown
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3904bp between positions 75735261-75739164 of Chromosome 15 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Gsdmd Mutation: 32 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 1 reference(s)