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b2b954Clo
Chemically induced Allele Detail
Nomenclature
Symbol: b2b954Clo
Name: Mutant line 954; Bench to Bassinet Program (B2B/CVDC), mutation 954 Cecilia Lo
MGI ID: MGI:5311368
Synonyms: Rudolph
Gene: b2b954Clo  Location: unknown  
Nasal hemorrhage

Show the 13 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: B2B/CvDC
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Undefined
    This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any b2b954Clo Mutation:  1 strain or line available
Notes
Summative Diagnosis:
Cardiovascular defects: Persistent truncus arteriosus (PTA) Type I and aortic arch anomalies such as right aortic arch (RAA), vascular ring and ventricular septal defect (VSD)
Noncardiovascular defects: Thymic hypoplasia and nasal hemorrhage.

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID Code Description
0500 Truncus arteriosus
1300 Ventricular septal defect
2720 Right aortic arch
2760 Vascular ring
3804 Congenital heart disease
4610 DiGeorge syndrome
4906 Non-cardiac abnormality

References
Original:  J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-15;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory