Tg(RP23-159N6*)43Bdm
Transgene Detail

Summary

• Symbol: Tg(RP23-159N6*)43Bdm
• Name: transgene insertion 43, Bernard de Massy
• MGI ID: MGI:5311010
• Synonyms: Tg(wm7)
• Transgene: Tg(RP23-159N6*)43Bdm Location: unknown
• Alliance: Tg(RP23-159N6*)43Bdm page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(RP23-159N6*)43Bdm expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Prdm9 (MGI:2384854)

• Mutation details: The transgene contains BAC RP23-159N6, in which the zinc finger domain of Prdm9 (coordinates: Chromosome 17, 15680882-15682252, NCBI m37 mouse genome assembly) has been replaced with the zinc finger domain from the Prdm9 allele of strain B10.A(R209)(Prdm9^wm7). Line 2 was generated. (J:180577)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:180577 Grey C, et al., Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination. PLoS Biol. 2011 Oct;9(10):e1001176
• All: 3 reference(s)