Vezf1^tm2Stmn
Targeted Allele Detail

Summary

• Symbol: Vezf1^tm2Stmn
• Name: vascular endothelial zinc finger 1; targeted mutation 2, Heidi Stuhlmann
• MGI ID: MGI:5308449
• Synonyms: Vezf1^lacZ
• Gene: Vezf1 Location: Chr11:87959105-87975555 bp, + strand Genetic Position: Chr11, 52.4 cM

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector replaced exon 1 and the proximal part of the first intron with an SDK-lacZ-PGKneo cassett. The translation initiation site was restored. (J:180860)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vezf1 Mutation: 27 strains or lines available

References

• Original: J:180860 Zou Z, et al., Targeted Vezf1-null mutation impairs vascular structure formation during embryonic stem cell differentiation. Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1378-88
• All: 1 reference(s)