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Tg(Fabp2-CFTR*)1Wsh
Transgene Detail
Nomenclature
Symbol: Tg(Fabp2-CFTR*)1Wsh
Name: transgene insertion 1, Michael J Welsh
MGI ID: MGI:5308021
Synonyms: CFTRdeltaR
Transgene: Tg(Fabp2-CFTR*)1Wsh  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL/J)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Fabp2-CFTR*)1Wsh expresses 1 gene
 
Mutation detailsNucleotides -1178 to +28 of the rat intestinal fatty acid binding protein (Fabp2) promoter drive expression of a human CFTR cDNA from which sequences encoding N-terminal residues 708-759 have been deleted. Line 1 was generated. (J:169220)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:169220 Ostedgaard LS, et al., Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2921-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory