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Targeted Allele Detail
Symbol: Npy1rtm1.1Ceva
Name: neuropeptide Y receptor Y1; targeted mutation 1.1, Carola Eva
MGI ID: MGI:5307897
Synonyms: Npy1r2lox, Npy1rloxP
Gene: Npy1r  Location: Chr8:66697422-66706798 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Germline Transmission:  Earliest citation of germline transmission: J:180396
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsAn FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette and left the coding sequence floxed. (J:180396)
Generation of the Npy1rtm1.1Ceva and Npy1rtm1.2Ceva alleles
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:  10 strains or lines available
Original:  J:180396 Bertocchi I, et al., Regulatory functions of limbic Y1 receptors in body weight and anxiety uncovered by conditional knockout and maternal care. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19395-400
All:  2 reference(s)

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MGI 6.04
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