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Tg(CAG-Epha4/Efna5,-mCherry)1Slp
Transgene Detail
Nomenclature
Symbol: Tg(CAG-Epha4/Efna5,-mCherry)1Slp
Name: transgene insertion 1, Samuel L Pfaff
MGI ID: MGI:5307247
Synonyms: EphA4ECD-ephrin-A5GPI
Transgene: Tg(CAG-Epha4/Efna5,-mCherry)1Slp  Location: unknown  
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsFLAG-tagged chicken EphA4 extracellular domain (ECD) fused to the glycosylphosphatidylinositol (GPI) anchor signal of Efna5 was placed under the control of a chicken beta actin/CMV (CAG) promoter behind a floxed stop cassette. The Epha4ECD-Efna5GPI cDNA is followed by an IRES signal driving expression of monomeric membrane-associated cherry fluorescent protein (mCherry). (J:180801)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:180801 Bonanomi D, et al., Ret Is a Multifunctional Coreceptor that Integrates Diffusible- and Contact-Axon Guidance Signals. Cell. 2012 Feb 3;148(3):568-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory