Trip12^tm2Jyan
Targeted Allele Detail

Summary

• Symbol: Trip12^tm2Jyan
• Name: thyroid hormone receptor interactor 12; targeted mutation 2, Junn Yanagisawa
• MGI ID: MGI:5307152
• Synonyms: mt #2
• Gene: Trip12 Location: Chr1:84698910-84818237 bp, - strand Genetic Position: Chr1, 43.42 cM, cytoband F

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: FLAG and HA epitope tags were fused to exon 32 and exon 33 was replaced with an IRES and hygro cassette. The predicted protein lacks the catalytic core of the HECT domain. (J:179766)

Generation of the Trip12^tm2Jyan allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trip12 Mutation: 168 strains or lines available

References

• Original: J:179766 Kajiro M, et al., The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis. PLoS One. 2011;6(10):e25871
• All: 1 reference(s)