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Casrtm1Wch
Targeted Allele Detail
Nomenclature
Symbol: Casrtm1Wch
Name: calcium-sensing receptor; targeted mutation 1, Wenhan Chang
MGI ID: MGI:5306665
Synonyms: Casrflox
Gene: Casr  Location: Chr16:36493696-36562141 bp, - strand  Genetic Position: Chr16, 25.57 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:180651
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA floxed neo cassette was inserted upstream of exon 7. An additional loxP site was inserted downstream of exon 7. (J:180651)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Casr Mutation:  6 strains or lines available
References
Original:  J:180651 Chang W, et al., The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2008;1(35):ra1
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory