About   Help   FAQ
Tg(Prm1-sb16)BFsp
Transgene Detail
Summary
Symbol: Tg(Prm1-sb16)BFsp
Name: transgene insertion B, Francois Spitz
MGI ID: MGI:5305593
Transgene: Tg(Prm1-sb16)BFsp  Location: unknown  
Alliance: Tg(Prm1-sb16)BFsp page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Transposase)
Mutation:    Insertion
 
Mutation detailsThe mouse Prm1 promoter drives expression of a hyperactive form of the sleeping beauty transposes. The hyperactive transposase contains the point mutations K13A, K33A, T83A, A205K, HK207VR, D210E. Transposase activity of sb16 is about 16 fold higher than that of sb15. (J:180121)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:180121 Ruf S, et al., Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011 Apr;43(4):379-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory