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Pomt2tm1.1Hhu
Targeted Allele Detail
Nomenclature
Symbol: Pomt2tm1.1Hhu
Name: protein-O-mannosyltransferase 2; targeted mutation 1.1, Huaiyu Hu
MGI ID: MGI:5302103
Gene: Pomt2  Location: Chr12:87106866-87147902 bp, - strand  Genetic Position: Chr12, 41.3 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:179356
Parent Cell Line:  D2 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6J)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed. (J:179356)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pomt2 Mutation:  6 strains or lines available
References
Original:  J:179356 Hu H, et al., Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. J Comp Neurol. 2011 May 1;519(7):1320-37
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory